Co-Enzyme Q₁₀, also known as CoQ or ubiquinone, is an important vitamin-like nutrient referred to by some researchers as "the miracle nutrient" and "the nutrient of the 90’s" because of the positive results seen in research done with a variety of diseases and conditions.

Co-Q₁₀ resembles vitamin E and vitamin K in chemical structure. Biochemically it functions much like vitamin E in that it participates in antioxidant and free radical reactions. However, Co-Q₁₀ has a special biochemical role of major importance...it plays a critical role in the production of ATP, the basic energy molecule of all cells.

Co-Enzyme Q₁₀ is essential to life. According to projections based on autopsies of diseased human hearts and biopsies from healthy hearts and other organ and tissue samples, once internal levels of Co-Q₁₀ drop below 25% of normal, disease is likely to ensue. If levels drop to a 75% deficiency, death will probably follow as a natural course.

Although the body can absorb Co-Q₁₀ from foods or synthesize the nutrient from other co-enzymes (Q₁ through Q₉), that ability declines through the normal process of aging as do body levels of Co-Q₁₀. Restoration of youthful Co-Q₁₀ levels through supplementation has been shown to correct many diseases associated with the aging process.

Animal studies by Dr. Emile Bliznakov, scientific director of the Lupus Research Institute in Ridgefield, CT, have shown that the mean life span can be increased by as much as 50% through Co-Q₁₀ supplementation. More importantly, the longer living animals remained more active and younger looking with bright eyes, glossy coats and healthy skin. And, their more youthful appearance lasted right up to the end of their lives.

More Co-Q₁₀ is found in the heart tissue than in any other muscle in the body. According to Dr. Karl Folkers, the "father" of Co-Q₁₀ research in the United States, most heart patients show a significant deficiency of Co-Q₁₀. Research, conducted by Dr. Folkers and confirmed by numerous other researchers around the world, has shown remarkable improvement in patients suffering from congestive heart failure, myocardial ischemic disorder and angina pectoris when given supplements of Co-Q₁₀.

Co-Q₁₀ has also been shown to have a stabilizing effect on heart rhythm. Dr. Folkers believes that Co-Q₁₀ deficiency may even be a major cause of heart disease and that prophylactic use of the nutrient may prevent many human heart problems.

Although the role of Co-Q₁₀ in the normalization of blood pressure is not fully understood, animal and clinical studies have shown that the nutrient can, indeed, lower elevated blood pressure.

A distinct connection has been observed between Co-Q₁₀ deficiencies as well as elevated ratio of sodium to potassium in the blood and tissues of high blood pressure patients. With Co-Q₁₀ therapy, the ratio of sodium to potassium decreases. This action is much like the beneficial effect seen when high blood pressure patients remove salt (sodium) from their diets.

Tests also show that Co-Q₁₀ supplementation has no effect at all on blood pressure levels of individuals with normal blood pressure.

Scientist now attach crucial importance to the link between the immune system and aging. A series of experiments by Bliznakov and others show that Co-Q₁₀ supplementation can:

• Double the immune system’s ability to clear invading organisms from the blood.
• Double antibody levels.
• Protect against chemically induced cancer (fewer and smaller tumors and increased survival times).
• Increase resistance to viral infections.
• Reduce the toxicity of immunosuppressive drugs used in cancer treatment.
• Quench free radicals associated with arthritis and other chronic degenerative diseases.

The importance of stimulating the immune system cannot be overstated. A strong immune system can protect us from many diseases, from colds to cancer.

Impressive new Co-Q₁₀ research involves not only the immune system — with diseases such as diabetes, muscular dystrophy, multiple sclerosis and lupus erythematosus — it also involves Co-Q₁₀‘s beneficial role in treating allergies, asthma and other respiratory conditions as well as potential for treating anomalies of mental function such as schizophrenia and even Alzheimer’s disease.

One in four people in the United States will lose all their teeth to periodontal disease by age 60 and 90% of all Americans will suffer from it during their lifetimes. Studies conducted by Dr. Karl Folkers of the University of Texas and periodontal specialist Dr. Edward G. Wilkinson have shown that, unlike healthy oral tissue, cells in victims of periodontal disease are markedly deficient in Co-Q₁₀.

When Co-Q₁₀ was added to the diets of patients suffering from periodontal conditions, some results were dramatic. Not only was the progression of the disease halted, but gums that were once diseased and bleeding began to show clinically significant reversal of the disease process.

One case history involved an elderly woman who had not been able to eat solid foods for months because of intense pain. She was a "no hope" case. After 14 days of Co-Q₁₀ supplementation, the pain diminished and she was eating solids. Three months later her gums were a healthy pink and showed an almost complete reversal of the disease state.

Recent research into the causes of obesity has shown that one factor affecting metabolic rate is the amount of body heat generating brown adipose (fat) tissue. Thin people seem to waste more calories as heat while fat people tend to efficiently conserve calories and store them as fat. Since Co-Q₁₀ is critical to cell energy production and, thus, the production of body heat, it is reasonable to expect that body Co-Q₁₀ levels affect the storage of body fat.

Clearly, Co-Q₁₀ is a weight-loss aid to those who are deficient in the nutrient. In a Belgian study of 27 obese patients, Dr. Luc Van Gaal found that over half of the persons studied were significantly deficient in Co-Q₁₀. Dr. Van Gaal and his colleagues then performed a clinical study on two groups of overweight subjects. Subjects in group A were found to be deficient in Co-Q₁₀ while subjects in group B were not. Both groups were placed on controlled reducing diets and both were given 100 mg. of Co-Q₁₀ daily. After 9 weeks Group A had lost an average of 30 pounds compared to an average of 13 pounds for group B. After 3 months the Co-Q₁₀ deficient group had lost an average of 38 pounds.

Because Co-Q₁₀ is intimately involved with energy production, it is not surprising that benefits have been reported by body builders and other athletes. In a test involving sedentary young men on an exercise bike, performance parameters increased 12% for medium heart stress conditions to 28% for maximal heart stress after 8 weeks of Co-Q₁₀ supplementation and there was even significant improvement in resting heart function. Several performance parameters were measured including work capacity, maximal oxygen consumption and oxygen transport. No changes were made in the men’s diet or exercise habits other than the Co-Q₁₀ supplementation.

WARNING: This publication and the product contained in this publication has not been approved or evaluated by the Food and Drug Administration. This publication, and the product contained herein, are not intended to diagnose, treat, cure or prevent any disease or condition. The product relates to nutritional support only.

1. Bliznakof, E., Hunt, G., The Miracle Nutrient Coenzyme Q10, Bantam, 1987.

Fahy, G.M., "Life Extension Benefits of Coenzyme Q10", Antiaging News, Vol. 3, No. 7, pp. 74-8, July, 1983.

Folkers, K, et. al., Biomedical and Clinical Aspects of Coenzyme Q (Vols. 1-4), Elsevier Science Publishers, 1977, 1980, 1981, 1984.

Passwater, R., Coenzme Q10: "The Nutrient of the 90’s", Whole Foods, April, 1987.

2. Bliznakov, E.G., Casey, A. and Premuzic, E, "Coenzymes Q: Stimulants of Phagocytic Activity in Rats and Immune Response in Mice", Experientia, Vol. 26, pp. 953-4, 1970.

Downs, R., "Coenzyme Q10", Bestways, June, 1987.

3. Yamasami, T., Shibata, N., Folkers, K., "Bioenergetics in Clinical Medicine. Studies on coenzyme Q10 and essential hypertension", Res. Commun. Chem. Pathol. Pharmacol., 2:237-88, 1975.

4. Folkers, K., Sartori, M., Baker, L. and Richardson, P., "Observations of Significant Reductions of Arrhythmias in Treatment with Coenzyme Q10 of Patients Having Cardiovascular Disease", IRCS Medical Science 10, pp. 348-349, 1982.

Folkers, K., Vadhanavikit, S. and Mortensen, S,A., "Biochemical Rationale and Myocardial Tissue Data on the Effective Therapy of Cardiomyopathy and Coenzyme Q10", Proc. Natl. Acad. Sci., Vol. 62, pp. 901-4, Feb., 1985.

Hunt, G.L., "Miracle Nutrient?" Omni Magazine, Feb., 1987.

Langsjoen, P., Proceed. Nat. Acad. Sci. 82:4240-44, June, 1985.

5. Wilkinson, E., Arnold, R., Folkers, K., "Bioenergetics in Clinical Medicine VIII. Adjunctive Treatment of Periodontal Disease with Co-Enzyme Q10", Res. Commun. Chem. Pathol. Pharmacol., 4:715-9, 1976.

6. Van Gaal, L., DeLeeuw, I., Vadhanavikit, S., Folkers, K., "Exploratory Study of Coenzyme Q10 in Obesity. Biomedical and Clinical Aspects of Coenzyme Q", Vol. 4, pp. 369-73, Elsevier Science Publishers B.V., 1984.

Product No. 853 Fill Size: 60 tablets

Each tablet contains: 25 mg. of pure, natural Co-Enzyme Q10.

Other ingredients: sorbitos, mannitol, silicon dioxide, magnesium stearate, orange flavor, citric acid, sodium citrate.

Recommended Usage: One to four tablets daily. Tablets may be dissolved in the mouth, under the tongue, chewed or swallowed whole.